Actually, no.
The pythons and alligators stand absolutely no chance against them — they frequently target crocodiles and are way too big for the pythons.
Hippos are one of the most dangerous animals on the planet and the single most dangerous animal on the African continent.
They are the third-largest land mammal in the World (males averaging 3,310 lb, but weighing up to 5,860lbs in the wild and 9,920lbs in captivity) … can run around 19mph … ‘swim’ around 15mph … have ridiculously sharp (1' 8" long) teeth and massively strong jaws (the bite force of an adult female hippo has been measured as 8.1 kN / 1,800 lbf) in a (up to) four foot wide mouth which can be opened up to almost 180° … and are responsible for more human deaths on the African continent than any other large animal — over 500 per year (twice as many as lions).
They are unpredictable and aggressive … unafraid of humans, they will attack both cars and boats without provocation … and are the World’s deadliest land mammal.
Do not fuck with hippos … they will eat you alive